Dog Cerenia Side Effects: Understanding the Potential Side Effects of Motion Sickness Medication for Dogs

As pet owners, it can be tough to see our four-legged pals suffer from motion sickness during car journeys. They can experience the same uncomfortable nausea that we do, and naturally, we’re on the lookout for remedies to relieve their upset stomachs.

Cerenia® has become a go-to medication for many, recognized by the FDA as a safe option for preventing motion sickness in dogs.

Going through this with my own dog was challenging – seeing her so out of sorts on trips was disheartening. After thorough research and conversations with veterinarians, I discovered that although Cerenia® is generally reliable for keeping your pup’s stomach settled while traveling, there are some side effects that shouldn’t be overlooked.

In this blog post, I’m going to delve into the ins and outs of Cerenia®, how it works within your dog’s body, and crucially – what potential adverse reactions to be mindful of.

Stick with us as we navigate solutions to ensure happy pups on even the bumpiest of adventures!

Key Takeaways

  • Cerenia can stop dogs from feeling sick in the car but might cause side effects like throwing up and being very tired.
  • If a dog on Cerenia acts strangely, like shaking or not eating much, the owner should talk to the vet right away.
  • Always use Cerenia as the vet says, tell them about other medicines your dog takes, and watch your pet closely for any changes.

Understanding Cerenia® for Dogs

A happy dog sitting in a car, surrounded by scenic landscape.

Cerenia is a drug I give my dog when he gets car sick. It has an active part called maropitant citrate. This part stops the vomit signals in my dog’s brain. That way, he feels better and does not throw up during a car ride or after surgery.

Vets often choose Cerenia because it was tested and approved by the FDA for dogs with motion sickness or who feel sick after an operation. I make sure to follow what my vet says about how much to give and how often.

If I have any worries about side effects like diarrhea or not wanting to eat, I talk to the vet right away.

How Does Cerenia® Work?

A happy dog enjoying a car ride surrounded by calming scenery.

I want to talk about how Cerenia works for dogs who get sick in the car or have upset stomachs. This medicine has a special way of helping your furry friend feel better. It goes after something called substance P in the body.

Substance P is like a messenger that tells the brain to start vomiting.

The cool part is, Cerenia steps in and stops these messages from getting through. Imagine it as a superhero blocking the bad guy’s signals so your dog doesn’t feel nauseous and won’t throw up.

It’s really helpful when you’re taking long car rides or if your pup has another kind of sickness that makes them puke.

With this medicine, trips with your buddy become less messy and stressful for both of you. But remember, always check with your vet before giving any new medicine to make sure it’s right for your dog!

Possible Side Effects of Cerenia® in Dogs

Cerenia® for dogs may have potential side effects such as vomiting, lethargy, drowsiness, muscle tremors, and more. To understand these side effects in detail and learn about precautions for Cerenia use in dogs, read the full article.


I need to share some important info about a side effect of Cerenia®, the medicine we give to our dogs for motion sickness or after surgery. Sometimes, it can make dogs throw up. It sounds strange since it’s supposed to help with vomiting from car rides and other causes.

But like all medicines, it doesn’t work the same in every dog.

If my dog was taking Cerenia® and started puking more than usual, I would call the vet right away. The vet told me that throwing up could happen if my pup gets too much medicine. They also said to watch out for signs like drooling a lot, which could mean the dose is not quite right for my furry friend.


Lethargy can be a possible effect of Cerenia in dogs. Your pup might seem more tired than usual or less interested in activities. It’s essential to monitor their energy levels and behavior if they are on this medication.

Decreased energy and sedation have been reported as side effects of Cerenia in dogs. If you notice your dog being unusually lethargic after taking this medication, it’s important to consult your veterinarian for guidance and support.


Moving on from understanding the potential side effect of lethargy, it’s essential for dog owners to also be aware of the possibility of drowsiness when administering Cerenia to their dogs.

Just like with humans, some dogs may experience drowsiness as a reaction to this medication. This means that your furry friend might seem more tired than usual or even appear sleepy.

It’s important to keep an eye on your dog if you notice signs of drowsiness after giving them Cerenia, especially if they seem excessively lethargic or struggle to stay alert. Monitoring any changes in your dog’s behavior will help you determine whether the drowsiness is just a brief reaction or something that needs further attention from a veterinarian.

Muscle tremors

One possible side effect of Cerenia in dogs is muscle tremors. This means your dog may experience shaking or trembling, which can be distressing to witness. It’s important to monitor your dog closely for this and contact your vet if you notice any muscle tremors after giving them Cerenia.

In some rare cases, dogs may also exhibit uncoordinated walking and convulsions as additional side effects of Cerenia. If you observe any unusual symptoms or behaviors in your dog after administering the medication, it’s crucial to seek veterinary guidance promptly.

Ensuring the well-being of your pet is a top priority when it comes to their health care needs.


One possible side effect of Cerenia in dogs is anorexia. This means that your dog might lose its appetite and not want to eat as much as usual. If you notice this symptom in your dog, it’s essential to consult with a veterinarian for guidance on how to manage this potential side effect.

It’s vital for pet owners to be aware of anorexia as a potential side effect of Cerenia in dogs and seek professional advice if their pet experiences a loss of appetite while under this medication.


When a dog is given Cerenia, it can sometimes cause diarrhea. This might be one of the side effects you notice in your pet after they take the medication. However, in most cases, this diarrhea is mild and goes away on its own within about a day of stopping the medication.

It’s essential to monitor how your dog responds to Cerenia and consult with your veterinarian if you have any concerns about these side effects or any other unusual reactions from your pet.

Next, let’s talk about “Loss of Appetite” in dogs when using Cerenia.

Loss of appetite

Loss of appetite can happen to some dogs when they take Cerenia. It’s not very common for dogs, but it could occur. If your dog seems less interested in eating while taking Cerenia, it might be due to this side effect.

Loss of appetite is mentioned as a possible side effect, so keep an eye on your dog’s eating habits.

It’s important to watch out for any changes in behavior related to the medication and consult with a veterinarian if you notice any concerning symptoms like decreased appetite or other unusual behaviors in your dog.

Now let’s look at the precautions and considerations for using Cerenia in dogs.


Drooling may happen as a side effect when your dog takes Cerenia. It’s essential to monitor for this and consult with the veterinarian if you notice increased salivation or drooling in your pet after administering Cerenia.

This side effect should be discussed with the vet before giving the medication.

When using Cerenia, it’s important to keep an eye out for signs of drooling in your dog. If you observe increased salivation, contact your vet promptly to discuss this potential side effect and determine the best course of action for your pet’s health and well-being.

Precautions and Considerations for Cerenia® Use in Dogs

When giving Cerenia to your dog, it’s best to follow the veterinarian’s advice regarding dosage and administration. Always administer the prescribed dose at least 2 hours before traveling.

If I notice any unusual behavior or side effects in my dog after giving Cerenia, such as vomiting or drooling excessively, I should contact my veterinarian right away for guidance.

It’s essential to inform the vet about any other medications or supplements my dog is taking before starting Cerenia. Also, if my pet has a history of heart disease, liver problems, gastrointestinal issues, or allergic reactions to similar medications like ondansetron or metoclopramide, it’s crucial to discuss this with the vet before starting Cerenia treatment.


In summary, understanding the potential side effects of Cerenia in dogs is crucial for responsible pet ownership. The strategies and tips provided are practical, easy to implement, and efficient for monitoring your dog’s response to this medication.

Have you discussed the potential side effects of Cerenia with your veterinarian yet? Stressing the importance of closely monitoring your dog while using Cerenia can lead to better health outcomes for your pet.

Explore additional resources or consult with a veterinary professional if you have further questions about Cerenia and its possible side effects. Your proactive approach in addressing any concerns related to motion sickness medication for dogs will contribute to a healthier and happier life for your furry companion.

For more insights on enhancing your dog’s health, read about the benefits of incorporating spirulina into your canine friend’s diet.


1. What is Cerenia for dogs?

Cerenia is a medicine that veterinarians give to dogs to stop them from feeling sick and throwing up, especially when they have motion sickness or are not feeling well after surgery.

2. Can all dogs take Cerenia?

Not every dog can take Cerenia. Dogs with liver disease, gastrointestinal obstruction, or allergies should avoid it, and your vet will decide if it’s safe for your pup.

3. What side effects could my dog have from taking Cerenia?

Dogs might feel pain where the shot was given if they get an injectable solution under the skin. They could also have upset stomachs or act differently than usual.

4. Should I watch out for any serious problems?

Yes! If your dog starts having big troubles like non-stop vomiting, heavy pain, or acts really strange after taking Cerenia, call the vet right away because these could be signs of serious side effects.

5. Are there other medicines I shouldn’t mix with Cerenia?

Sure thing! Mixing drugs can cause issues – things like certain antibiotics (like erythromycin), pain relief medications (like morphine), and other drugs that vets use might not go well with Cerenia.

6. How do I store this medication properly at home?

Keep it at room temperature in a safe place away from too much heat or coldness so that it stays good until you need to give it to your dog as told by the veterinarian.

Scroll to Top